Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 20/20 | 0.71 |
| ▸ | KCNK9 | Q9NPC2 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20588935 | 0.93 | KCNK3 (0.68) | KCNK3KCNK9 | |
| SCHEMBL30359141 | 0.90 | KCNK3 (0.65) | KCNK3KCNK9 | |
| SCHEMBL22001579 | 0.83 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL30359166 | 0.83 | KCNK3 (0.69) | KCNK3KCNK9 | |
| SCHEMBL22636283 | 0.83 | KCNK3 (0.70) | KCNK3KCNK9 | |
| SCHEMBL25291133 | 0.83 | KCNK3 (0.65) | KCNK3KCNK9 | |
| SCHEMBL30417973 | 0.82 | KCNK3 (0.69) | KCNK3KCNK9 | |
| SCHEMBL21826380 | 0.82 | KCNK3 (0.79) | KCNK3KCNK9 | |
| SCHEMBL20590106 | 0.81 | KCNK3 (0.88) | KCNK3KCNK9 | |
| SCHEMBL22001480 | 0.81 | KCNK3 (0.64) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118541153-A | Conjugates of a TASK1/3 channel blocker and a norepinephrine reuptake inhibitor for the treatment of sleep apnea | 拜耳公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118434415-A | Conjugates of TASK1/3 channel blockers and muscarinic receptor antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-08-02 | — | — | CN | claimed |
| CN-118785904-A | Conjugates of TASK1/3 channel blockers and P2X3 receptor antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118541153-A | Conjugates of a TASK1/3 channel blocker and a norepinephrine reuptake inhibitor for the treatment of sleep apnea | 拜耳公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118434415-A | Conjugates of TASK1/3 channel blockers and muscarinic receptor antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-08-02 | — | — | CN | disclosed |
| WO-2023118126-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A NOREPINEPHRINE REUPTAKE INHIBITOR FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023118122-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A P2X3 RECEPTOR ANTAGONIST FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-29 | — | — | WO | disclosed |