Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25720884 | 0.91 | HSP90AA1 (0.47) | HSP90AA1ALOX15NPY5RHTR1AHTR1D | |
| Formic Acid SCHEMBL25280406 | 0.88 | HSP90AA1 (0.56) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL24054698 | 0.88 | HSP90AA1 (0.59) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL25279070 | 0.87 | HSP90AA1 (0.47) | HSP90AA1ALOX15NPY5RHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL30198181 | 0.87 | HSP90AA1 (0.58) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL25280205 | 0.87 | HSP90AA1 (0.58) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL25233340 | 0.83 | MEN1 (0.46) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL24054806 | 0.81 | HSP90AA1 (0.59) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL28985734 | 0.81 | HSP90AA1 (0.58) | HSP90AA1ALOX15MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL30198398 | 0.81 | HSP90AA1 (0.58) | HSP90AA1ALOX15MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
| CN-115836056-A | NOTCH inhibitors and uses thereof | STEMSYNERGY疗法有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | HSP90AA1 4749/4885ALOX15 1130/4885NPY5R 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.