Profenofos

Profenofos

SCHEMBL25281

CCCSP(=O)(OCC)Oc1ccc(Br)cc1Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 1/20 0.39
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.37
KDM4E B2RXH2 1/20 0.36
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Profenofos SCHEMBL29420096 1.00 MEN1 (0.52) MEN1KMT2ATSHRTDP1HPGD
Profenofos SCHEMBL6732594 1.00 MEN1 (0.52) MEN1KMT2ATSHRTDP1HPGD
Profenofos SCHEMBL29142110 0.99 MEN1 (0.51) MEN1KMT2ATSHRTDP1HPGD
Profenofos SCHEMBL8465347 0.96 KMT2A (0.49) MEN1KMT2ATSHRTDP1HPGD
Profenofos SCHEMBL28827325 0.96 KMT2A (0.49) MEN1KMT2ATSHRTDP1HPGD
Profenofos SCHEMBL29054443 0.91 KMT2A (0.45) MEN1KMT2ATSHRTDP1HPGD
SCHEMBL11788990 0.88 MEN1 (0.53) MEN1KMT2ATDP1HPGDRAB9A
Profenofos SCHEMBL27463154 0.88 KMT2A (0.43) MEN1KMT2ATSHRTDP1HPGD
SCHEMBL10895157 0.87 MEN1 (0.41) MEN1KMT2ASMN1; SMN2
SCHEMBL115562 0.87 MEN1 (0.68) MEN1KMT2ATSHRTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27216 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
EP-4723893-A2 COMPOSITIONS AND METHODS TO MITIGATE PHYTOTOXIC EFFECTS OF AGRICHEMICALS Ascribe Bioscience Inc. (US) 2026-04-15 EP claimed
EP-4719059-A1 INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS Bio Logic Crop Science, S.L. (ES) 2026-04-08 EP claimed
US-20260083129-A1 PYRAZOLE AMIDE INSECTICIDES FMC CORP (US) 2026-03-26 US claimed
US-20260083130-A1 NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2026-03-26 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 US claimed
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
EP-0369612-A1 Insecticidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-23 EP claimed
EP-0242502-A2 Pesticidal compositions HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-28 EP claimed
US-4584296-A BLEND OF 2-112.6-DIFLUOROPHENYL)ACYLUREA(3,5-DIFLUORO1,4-PHENYLEN)-/-),3-CHLORO-5 -TRIFLUOROMETHANOPYRIOINE WITH A HALOGENATED AROMATIC THIOPHOSPHATE CIBA-GEIGY CORPORATION (US) 1986-04-22 US claimed
EP-0068297-B1 A NEW INSECTICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE A. Nattermann & Cie. GmbH (DE) 1985-12-18 EP claimed
EP-0053101-B1 AGENTS PESTICIDES CIBA-GEIGY AG (CH) 1984-09-19 EP claimed
US-4436737-A PHENYLPHOSPHOROTHIOATES AND BENZIMIDAZOLECARBAMATES CIBA-GEIGY CORPORATION (US) 1984-03-13 US claimed
EP-0068297-A1 A new insecticidal composition, processes for its production and its use A. Nattermann & Cie. GmbH (DE) 1983-01-05 EP claimed
US-4251523-A WITH TOXAPHENE AND DDT, FOR USE ON COTTON PLANTS ROHM AND HAAS COMPANY (US) 1981-02-17 US claimed
EP-0017339-A1 Insecticidal synergistic composition containing O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(2-chloro-4-bromophenyl)-S-n-propyl phosphorothioate and method of controlling insects therewith THE DOW CHEMICAL COMPANY (US) 1980-10-15 EP claimed
US-4223026-A Insecticidal synergistic mixture of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(2-chloro-4-bromophenyl)-S-n-propyl phosphorothioate THE DOW CHEMICAL COMPANY (US) 1980-09-16 US claimed