Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439605 | 1.00 | CA1 (0.47) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL3500688 | 0.93 | CA1 (0.42) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL28459624 | 0.93 | CA1 (0.42) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL3500690 | 0.93 | CA1 (0.42) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL28459621 | 0.93 | CA1 (0.42) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL3503846 | 0.93 | CA1 (0.42) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL28976792 | 0.93 | CA1 (0.42) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL3503269 | 0.92 | CA1 (0.41) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL3503271 | 0.92 | CA1 (0.41) | CA1CA2CA7KMT2ACYP2D6 | |
| SCHEMBL22338809 | 0.91 | CA1 (0.51) | CA1CA2CA7KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |