Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 4/20 | 0.55 |
| ▸ | CES1 | P23141 | 4/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531498 | 0.97 | KMT2A (0.67) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL27807482 | 0.97 | KMT2A (0.67) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL28115930 | 0.97 | KMT2A (0.67) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL28589336 | 0.97 | KMT2A (0.67) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL94903 | 0.92 | — | — | |
| SCHEMBL2530667 | 0.90 | KMT2A (0.62) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL2533966 | 0.90 | KMT2A (0.62) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL45463 | 0.89 | KMT2A (0.75) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL17505343 | 0.89 | KMT2A (0.75) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL2529882 | 0.87 | KMT2A (0.67) | KMT2AMAPTCES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| CN-103025157-A | Compounds, methods, and devices for detecting and/or treating insect infestation | BAYER CROPSCIENCE LP | 2013-04-03 | — | — | CN | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| CN-102448949-B | Heterocyclic compound and hematopoietic stem cell amplifier | NISSAN CHEMICAL IND LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-103025157-A | Compounds, methods, and devices for detecting and/or treating insect infestation | BAYER CROPSCIENCE LP | 2013-04-03 | — | — | CN | disclosed |
| CN-102448949-A | Heterocyclic compound and hematopoietic stem cell amplifier | NISSAN CHEMICAL IND LTD | 2012-05-09 | — | — | CN | disclosed |
| CN-101072766-B | 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD | 2012-05-02 | — | — | CN | disclosed |
| CN-101076519-B | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL IND LTD | 2011-07-20 | — | — | CN | disclosed |
| CN-101889007-A | Method for expansion of hematopoietic stem cells using heterocyclic compound | NISSAN CHEMICAL IND LTD | 2010-11-17 | — | — | CN | disclosed |