Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.46 |
| ▸ | BTK | Q06187 | 11/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449270 | 0.98 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL25277694 | 0.95 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL30449101 | 0.95 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL25230192 | 0.93 | EGFR (0.53) | EGFRBTK | |
| SCHEMBL25284153 | 0.91 | EGFR (0.44) | EGFRBTK | |
| SCHEMBL30449840 | 0.85 | KMT2A (0.40) | BTK | |
| SCHEMBL25228606 | 0.85 | KMT2A (0.40) | BTK | |
| SCHEMBL25269942 | 0.81 | EGFR (0.54) | EGFRBTK | |
| SCHEMBL28710291 | 0.81 | EGFR (0.54) | EGFRBTK | |
| SCHEMBL25269684 | 0.81 | EGFR (0.55) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110970-A1 | MACROCYCLIC BTK INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |