⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL22440719 | 1.00 | TSHR (0.56) | — | |
| Triethylene Glycol SCHEMBL22440710 | 0.97 | MEN1 (0.58) | — | |
| SCHEMBL4852726 | 0.97 | MEN1 (0.58) | — | |
| Tetraethylene Glycol SCHEMBL22440716 | 0.97 | MEN1 (0.58) | — | |
| SCHEMBL30230572 | 0.97 | MEN1 (0.58) | — | |
| SCHEMBL18506589 | 0.97 | MEN1 (0.58) | — | |
| Ethylene Glycol SCHEMBL21802491 | 0.92 | TSHR (0.42) | — | |
| Ethylene Glycol SCHEMBL11808919 | 0.92 | TSHR (0.42) | — | |
| SCHEMBL10867212 | 0.90 | TSHR (0.43) | — | |
| SCHEMBL193470 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1215196-B1 | Selective reductive amination of nitriles | AIR PROD & CHEM (US) | 2004-05-12 | — | — | EP | claimed |
| EP-0913388-B1 | Hydrogenation of nitriles to produce amines | AIR PROD & CHEM (US) | 2003-10-01 | — | — | EP | claimed |
| EP-1215196-A1 | Selective reductive amination of nitriles | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-06-19 | — | — | EP | claimed |
| US-6399830-B1 | USING CATALYST | AIR PRODUCTS AND CHEMICALS, INC. | 2002-06-04 | — | — | US | claimed |
| US-6248925-B1 | REACTING A NITRILE WITH A PRIMARY OR SECONDARY AMINE EFFECTING CONVERSION OF THE NITRILE GROUP TO THE CORRESPONDING SECONDARY OR TERTIARY AMINE; PROMOTIONALLY EFFECTIVE AMOUNT OF A LITHIUM COMPOUND OR SODIUM CHLORIDE. | AIR PRODUCTS AND CHEMICALS, INC. | 2001-06-19 | — | — | US | claimed |
| EP-0913388-A1 | Hydrogenation of nitriles to produce amines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-05-06 | — | — | EP | claimed |
| US-5869653-A | USING SPONGE OR RANEY COBALT CATALYST; AMMONIA-FREE REACTION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-02-09 | — | — | US | claimed |
| EP-0467348-B1 | Acrylic copolymer rubber | TOSOH CORP (JP) | 1995-04-05 | — | — | EP | claimed |
| US-5219967-A | Random (meth)acrylate copolymers with one monomer having a cyano group; heat, cold and fuel oil resistance | TOSOH CORPORATION (JP) | 1993-06-15 | — | — | US | claimed |
| EP-0467348-A2 | Acrylic copolymer rubber | Tosoh Corporation (JP) | 1992-01-22 | — | — | EP | claimed |
| JP-5105713-A | — | — | None | — | — | JP | disclosed |
| EP-4736882-A2 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-3841098-B1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN SHANGHAI INC (CN) | 2026-01-14 | — | — | EP | disclosed |
| US-12410171-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | CULLGEN (SHANGHAI), INC. (CN) | 2025-09-09 | — | — | US | disclosed |
| CN-120209015-A | Preparation of 3- [ (3, 3-dimethoxy-2, 7-dioxa-3-silanon-9-yl) oxy ] propionitrile | 张家港市国泰华荣化工新材料有限公司 | 2025-06-27 | — | — | CN | disclosed |
| US-4470416-A | SURGICAL SUTURES AND LUBRICANTS | ETHICON, INC. (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0077036-A1 | Binding agent compositions | UNION CARBIDE CORPORATION (US) | 1983-04-20 | — | — | EP | disclosed |
| US-4333963-A | FOR SOLVENT RESISTANT ACRYLATE COATINGS | ROHM AND HAAS COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4209539-A | HYDRATION OF TOXIC CYANO GROUPS TO AMIDE | ANVER BIOSCIENCE DESIGN, INC. (US) | 1980-06-24 | — | — | US | disclosed |
| US-4046794-A | ANCHORING AGENTS ON GLASS | UNION CARBIDE CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |