Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745190 | 1.00 | PREP (0.52) | PREPACE2NPSR1TSHRL3MBTL1 | |
| SCHEMBL25759230 | 1.00 | PREP (0.52) | PREPACE2NPSR1TSHRL3MBTL1 | |
| SCHEMBL1875019 | 0.88 | PREP (0.54) | PREPACE2NPSR1TSHRL3MBTL1 | |
| SCHEMBL10310516 | 0.87 | PREP (0.49) | PREPACE2NPSR1TSHRL3MBTL1 | |
| SCHEMBL3011829 | 0.83 | PREP (0.56) | PREPACE2NPSR1TSHRL3MBTL1 | |
| SCHEMBL30415573 | 0.83 | SMN1; SMN2 (0.51) | PREPNPSR1 | |
| SCHEMBL10310512 | 0.83 | PREP (0.56) | PREPACE2NPSR1TSHRL3MBTL1 | |
| SCHEMBL25248996 | 0.83 | SMN1; SMN2 (0.51) | PREPNPSR1 | |
| SCHEMBL25759344 | 0.82 | ELANE (0.54) | PREPACE2KLK7KLK5HSD17B10 | |
| SCHEMBL27766855 | 0.82 | PREP (0.56) | PREPACE2NPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410131-B2 | Method for preparation of trans-n-benzyloxycarbonyl-(3-hydroxy-2-piperidinyl)-2-propanone as intermediate of halofuginone | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2025-09-09 | — | — | US | claimed |
| CN-113999164-B | Preparation method of halofuginone intermediate trans-N-benzyloxycarbonyl- (3-hydroxy-2-piperidinyl) -2-propanone | 诚达药业股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | claimed |
| WO-2023065610-A1 | PREPARATION METHOD FOR HALOFUGINONE INTERMEDIATE TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-ACETONE | 诚达药业股份有限公司 | 2023-04-27 | — | — | WO | claimed |
| CN-113999164-A | Preparation method of halofuginone intermediate trans-N-benzyloxycarbonyl- (3-hydroxy-2-piperidyl) -2-acetone | 诚达药业股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| US-12410131-B2 | Method for preparation of trans-n-benzyloxycarbonyl-(3-hydroxy-2-piperidinyl)-2-propanone as intermediate of halofuginone | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2025-09-09 | — | — | US | disclosed |
| US-12410131-B2 | Method for preparation of trans-n-benzyloxycarbonyl-(3-hydroxy-2-piperidinyl)-2-propanone as intermediate of halofuginone | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2025-09-09 | — | — | US | disclosed |
| CN-113999164-B | Preparation method of halofuginone intermediate trans-N-benzyloxycarbonyl- (3-hydroxy-2-piperidinyl) -2-propanone | 诚达药业股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-113999164-B | Preparation method of halofuginone intermediate trans-N-benzyloxycarbonyl- (3-hydroxy-2-piperidinyl) -2-propanone | 诚达药业股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| WO-2023065610-A1 | PREPARATION METHOD FOR HALOFUGINONE INTERMEDIATE TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-ACETONE | 诚达药业股份有限公司 | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410131-B2 | Method for preparation of trans-n-benzyloxycarbonyl-(3-hydroxy-2-piperidinyl)-2-propanone as intermediate of halofuginone | RPL22, TALDO1, THPO | PREP 1931/4885ACE2 2012/4885NPSR1 1558/4885 |
| US-20230192614-A1 | METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE | TALDO1, RPL22, RPS20 | PREP 1233/4885ACE2 2855/4885NPSR1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.