Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.58 |
| ▸ | CCND1 | P24385 | 20/20 | 0.58 |
| ▸ | CCND3 | P30281 | 20/20 | 0.58 |
| ▸ | CDK6 | Q00534 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782181 | 1.00 | CDK4 (0.58) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25781722 | 0.91 | CDK4 (0.60) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25781728 | 0.91 | CDK4 (0.60) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25242393 | 0.91 | CDK4 (0.60) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25781729 | 0.91 | CDK4 (0.60) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25248785 | 0.90 | CDK4 (0.61) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25781734 | 0.90 | CDK4 (0.61) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25294211 | 0.88 | CDK4 (0.59) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25781732 | 0.88 | CDK4 (0.59) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL25254178 | 0.87 | CDK4 (0.58) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116862-A1 | HYDROGENATED INDOLE COMPOUND, AND PREPARATION METHOD AND MEDICAL USE THEREFOR | 江苏恒瑞医药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023116862-A1 | HYDROGENATED INDOLE COMPOUND, AND PREPARATION METHOD AND MEDICAL USE THEREFOR | 江苏恒瑞医药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |