Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259887 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11737353 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11735533 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2527274 | 0.98 | MEN1 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2527388 | 0.91 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28540701 | 0.91 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2533553 | 0.91 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2523632 | 0.91 | TSHR (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL13997537 | 0.88 | MEN1 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2528035 | 0.88 | MEN1 (0.41) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| US-4025641-A | INSECTICIDES, ACARICIDES | SANDOZ LTD. (CH) | 1977-05-24 | — | — | US | disclosed |