Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526451 | 0.98 | FFAR1 (0.46) | GPR84FFAR1FFAR4SMN1; SMN2KDM4E | |
| SCHEMBL2529087 | 0.98 | FFAR1 (0.46) | GPR84FFAR1FFAR4SMN1; SMN2KDM4E | |
| SCHEMBL2527740 | 0.93 | CAMK2A (0.42) | GPR84FFAR1FFAR4SMN1; SMN2KDM4E | |
| SCHEMBL2529497 | 0.82 | HMGCR (0.32) | TSHR | |
| SCHEMBL3751876 | 0.82 | FFAR1 (0.44) | GPR84FFAR1FFAR4SMN1; SMN2KDM4E | |
| SCHEMBL2528976 | 0.81 | MAPT (0.32) | KMT2AMAPT | |
| SCHEMBL11038929 | 0.79 | KMT2A (0.56) | GPR84FFAR1FFAR4TDP1KMT2A | |
| SCHEMBL2529084 | 0.79 | KMT2A (0.35) | GPR84FFAR1TDP1KMT2AMAPT | |
| SCHEMBL19617979 | 0.79 | KMT2A (0.56) | GPR84FFAR1FFAR4TDP1KMT2A | |
| SCHEMBL11519299 | 0.79 | KMT2A (0.56) | GPR84FFAR1FFAR4TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |