Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 11/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.50 |
| ▸ | CDC42 | P60953 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191431 | 0.90 | RB1 (0.62) | RB1GAACASP6BRD3CDC42 | |
| SCHEMBL22135853 | 0.90 | RB1 (0.62) | RB1GAACASP6BRD3CDC42 | |
| Hydrochloric Acid SCHEMBL15265307 | 0.89 | RB1 (0.63) | RB1GAACASP6BRD3CDC42 | |
| Hydrochloric Acid SCHEMBL4162946 | 0.89 | RB1 (0.63) | RB1GAACASP6BRD3CDC42 | |
| SCHEMBL16433492 | 0.88 | GAA (0.71) | RB1GAACASP6PRMT5BRD3 | |
| SCHEMBL31497433 | 0.88 | RB1 (0.57) | RB1GAACASP6BRD3CDC42 | |
| SCHEMBL31497425 | 0.88 | RB1 (0.57) | RB1GAACASP6BRD3CDC42 | |
| SCHEMBL4196258 | 0.87 | RB1 (0.54) | RB1GAACASP6PRMT5BRD3 | |
| Hydrochloric Acid SCHEMBL4153475 | 0.86 | RB1 (0.55) | RB1GAACASP6PRMT5BRD3 | |
| SCHEMBL5456604 | 0.86 | GAA (0.69) | RB1GAACASP6PRMT5BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |