Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22090497 | 0.93 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL22090501 | 0.93 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL30660031 | 0.93 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL24477825 | 0.92 | TSHR (0.38) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL22090713 | 0.89 | HPGD (0.41) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL28607190 | 0.88 | MEN1 (0.37) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL22090561 | 0.88 | HPGD (0.37) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL30659990 | 0.88 | HPGD (0.37) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL22090549 | 0.87 | MEN1 (0.42) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL22091050 | 0.85 | MEN1 (0.41) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894402-B1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2023-07-05 | — | — | EP | claimed |