Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | OTUB1 | Q96FW1 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252931 | 1.00 | PARP1 (0.34) | PARP1USP2USP1USP8OTUB1 | |
| SCHEMBL252929 | 1.00 | PARP1 (0.34) | PARP1USP2USP1USP8OTUB1 | |
| SCHEMBL9236438 | 0.85 | HPGD (0.36) | PARP1CHEK2 | |
| SCHEMBL8510897 | 0.79 | HPGD (0.38) | PARP1USP2 | |
| SCHEMBL8510894 | 0.79 | HPGD (0.38) | PARP1USP2 | |
| SCHEMBL8589188 | 0.77 | CDC7 (0.35) | PARP1 | |
| SCHEMBL249815 | 0.76 | HPGD (0.41) | USP2 | |
| SCHEMBL8510423 | 0.76 | HPGD (0.41) | USP2 | |
| SCHEMBL9233593 | 0.74 | CDC7 (0.39) | PARP1CHEK2 | |
| SCHEMBL655203 | 0.72 | PARP1 (0.34) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588478-A1 | AZAINDOLE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |