Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30548044 | 1.00 | HTR2A (0.49) | HTR2ASLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7866280 | 0.86 | SLC6A4 (0.64) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL30548025 | 0.86 | HTR2A (0.66) | HTR2AARPRKCBPRKCAPRKCH | |
| SCHEMBL25288178 | 0.86 | HTR2A (0.66) | HTR2AARPRKCBPRKCAPRKCH | |
| SCHEMBL25286351 | 0.76 | HTR2A (0.48) | HTR2A | |
| SCHEMBL25290977 | 0.76 | KDM4E (0.54) | HTR2ASLC6A4KDM4ELMNAPOLB | |
| SCHEMBL25248306 | 0.76 | HTR2A (0.47) | HTR2AKDM4ELMNAALOX15AR | |
| SCHEMBL25293430 | 0.74 | CHEK1 (0.45) | HTR2ASLC6A4KDM4ELMNAPOLB | |
| SCHEMBL16801563 | 0.74 | MAPT (0.50) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL25290621 | 0.72 | AR (0.46) | HTR2ASLC6A4KDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |