Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25297664 | 1.00 | MEN1 (0.51) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL24344785 | 0.90 | TDP1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL25253835 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL4428307 | 0.84 | C3AR1 (0.61) | MEN1KMT2AGAATDP1NPSR1 | |
| SCHEMBL4431865 | 0.82 | C3AR1 (0.54) | MEN1KMT2AGAATDP1NPSR1 | |
| SCHEMBL4426821 | 0.81 | C3AR1 (0.46) | MEN1KMT2AGAATDP1SUCNR1 | |
| SCHEMBL4427440 | 0.81 | C3AR1 (0.62) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL4437359 | 0.81 | C3AR1 (0.62) | MEN1KMT2AGAATDP1SUCNR1 | |
| SCHEMBL4429631 | 0.80 | C3AR1 (0.47) | MEN1KMT2AGAATDP1SUCNR1 | |
| SCHEMBL4427285 | 0.79 | C3AR1 (0.65) | MEN1KMT2AGAASUCNR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |