SCHEMBL25299658

SCHEMBL25299658

CC1C(I)CN1C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.36
HPGD P15428 1/20 0.35
EPHX2 P34913 1/20 0.35
HSD11B1 P28845 1/20 0.35
TSHR P16473 1/20 0.34
CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21227876 0.82 NR1H2 (0.42) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL27319966 0.82 NR1H2 (0.42) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL6418166 0.80 NR1H2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL23537846 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL21576383 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL25790119 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL23537845 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL23537641 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL29132955 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2
SCHEMBL19471685 0.79 CHRM2 (0.43) NR1H2CHRM2CHRM1CHRM3USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A NR1H2 926/4885CHRM2 3437/4885CHRM1 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.