Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305291 | 1.00 | AKR1C3 (0.36) | AKR1C3L3MBTL1KCNK3KIF11DRD2 | |
| SCHEMBL30491431 | 0.92 | AKR1C3 (0.33) | AKR1C3HRH3TSHR | |
| SCHEMBL30491427 | 0.88 | PRMT5 (0.33) | DRD2DRD3 | |
| SCHEMBL30491502 | 0.88 | GLRA1 (0.33) | DRD2DRD3 | |
| SCHEMBL30068848 | 0.88 | AKR1C3 (0.36) | AKR1C3L3MBTL1KIF11DRD2DRD3 | |
| SCHEMBL30491452 | 0.88 | BAZ2B (0.39) | KCNK3 | |
| SCHEMBL30491388 | 0.88 | GRM5 (0.34) | DRD2DRD3MEN1TSHRKMT2A | |
| SCHEMBL25306100 | 0.87 | — | — | |
| SCHEMBL25306095 | 0.87 | — | — | |
| SCHEMBL25253225 | 0.87 | GRM5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |