Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ozanimod. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 known ✓ | P21453 | 20/20 | 0.98 |
| ▸ | S1PR5 known ✓ | Q9H228 | 2/20 | 0.98 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.98 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.98 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.98 |
| ▸ | GPR183 | P32249 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ozanimod SCHEMBL30536287 | 1.00 | S1PR1 (0.98) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL29405708 | 1.00 | S1PR1 (0.98) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL20569961 | 1.00 | S1PR1 (0.98) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL2195490 | 0.99 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL1413256 | 0.99 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL29691988 | 0.99 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL30948381 | 0.99 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL2195471 | 0.99 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| Ozanimod SCHEMBL29560683 | 0.99 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL2212803 | 0.95 | S1PR1 (0.93) | S1PR1S1PR2S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997645-B | Preparation method of ozagrel | 埃吉斯制药公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-3630738-B1 | PROCESS FOR THE PRODUCTION OF OZANIMOD | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2023-07-19 | — | — | EP | disclosed |
| CN-110997645-A | Preparation method of ozanimod | 埃吉斯制药公司 | 2020-04-10 | — | — | CN | disclosed |