⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25307825 | 0.74 | SSTR4 (0.39) | — | |
| SCHEMBL127885 | 0.72 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL2879612 | 0.71 | GRM5 (0.31) | — | |
| SCHEMBL9102387 | 0.70 | — | — | |
| SCHEMBL22222428 | 0.68 | HRH1 (0.34) | — | |
| SCHEMBL20780321 | 0.68 | CCR4 (0.34) | — | |
| SCHEMBL22012330 | 0.68 | SRC (0.34) | — | |
| SCHEMBL22282771 | 0.65 | TLR7 (0.36) | — | |
| SCHEMBL12401743 | 0.65 | MEN1 (0.39) | — | |
| SCHEMBL4011022 | 0.65 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066360-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-02-27 | — | — | US | disclosed |
| EP-4464694-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-11-20 | — | — | EP | disclosed |
| CN-118525005-A | Polycyclic derivative containing pyridine, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118510776-A | Five-membered ring-containing derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023134765-A1 | FIVE-MEMBERED-RING-CONTAINING DERIVATIVES, PREPARATION METHOD THEREFOR, AND USES THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134764-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116444493-A | Derivative containing double parallel rings, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |