SCHEMBL25307309

SCHEMBL25307309

Cc1nccc(F)c1C1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
USP30 Q70CQ3 2/20 0.40
GPR119 Q8TDV5 7/20 0.40
CCNT1 O60563 1/20 0.40
CDK9 P50750 1/20 0.40
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
RORC P51449 1/20 0.39
AOC3 Q16853 1/20 0.39
POLB P06746 1/20 0.39
TRPV3 Q8NET8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31250365 1.00 KDM4E (0.41) KDM4EUSP30GPR119CCNT1CDK9
SCHEMBL25308411 0.85 CCNT1 (0.41) KDM4EUSP30GPR119CCNT1CDK9
SCHEMBL31250410 0.85 CCNT1 (0.41) KDM4EUSP30GPR119CCNT1CDK9
SCHEMBL31655123 0.82 KDM4E (0.41) KDM4EUSP30GPR119CCNT1CDK9
SCHEMBL25888628 0.82 KDM4E (0.41) KDM4EUSP30GPR119CCNT1CDK9
SCHEMBL24771291 0.81 KDM4E (0.48) KDM4EUSP30GPR119RORC
SCHEMBL31654894 0.78 CCNT1 (0.45) USP30CCNT1CDK9AOC3
SCHEMBL25888787 0.78 CCNT1 (0.45) USP30CCNT1CDK9AOC3
SCHEMBL31654465 0.78 PDE10A (0.47) KDM4EGPR119POLB
SCHEMBL25888854 0.78 PDE10A (0.47) KDM4EGPR119POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A KDM4E 1488/4885USP30 3192/4885GPR119 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.