Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408819 | 0.88 | NR4A2 (1.00) | NR4A2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL12918558 | 0.87 | NR4A2 (0.63) | NR4A2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL12386984 | 0.86 | NR4A2 (0.58) | NR4A2KMT2ALMNATP53MAPT | |
| SCHEMBL19407224 | 0.86 | NR4A2 (0.79) | NR4A2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL25238096 | 0.84 | NR4A2 (0.75) | NR4A2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL28241207 | 0.84 | NR4A2 (0.56) | NR4A2KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL15420904 | 0.83 | NR4A2 (0.79) | NR4A2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL25305334 | 0.80 | NR4A2 (0.51) | NR4A2KMT2ALMNATP53MAPT | |
| SCHEMBL17782624 | 0.80 | NR4A2 (0.61) | NR4A2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL15557161 | 0.80 | NR4A2 (0.72) | NR4A2KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460492-A1 | COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE | (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131677-A1 | COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-07-13 | — | — | WO | disclosed |