Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.51 |
| ▸ | CDK9 | P50750 | 7/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.50 |
| ▸ | CDK1 | P06493 | 12/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.50 |
| ▸ | CDK7 | P50613 | 11/20 | 0.50 |
| ▸ | CCNH | P51946 | 11/20 | 0.50 |
| ▸ | CDK4 | P11802 | 10/20 | 0.50 |
| ▸ | CCND1 | P24385 | 10/20 | 0.50 |
| ▸ | CCNK | O75909 | 2/20 | 0.50 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30518510 | 1.00 | CDK2 (0.51) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL25306155 | 0.87 | CDK2 (0.51) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL30518549 | 0.87 | CDK2 (0.51) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL30518524 | 0.86 | CDK2 (0.51) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL25306508 | 0.86 | CDK2 (0.51) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL25309353 | 0.83 | CDK1 (0.52) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL30518534 | 0.83 | CDK1 (0.52) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL25299779 | 0.83 | CDK1 (0.62) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL25309378 | 0.79 | CDK2 (0.56) | CDK2CCNA2CDK9CCNA1CCNT1 | |
| SCHEMBL30518560 | 0.79 | CDK2 (0.56) | CDK2CCNA2CDK9CCNA1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101023-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) | 2025-03-27 | — | — | US | claimed |
| WO-2023140640-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | 한양대학교 산학협력단 | 2023-07-27 | — | — | WO | claimed |
| US-20250101023-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) | 2025-03-27 | — | — | US | disclosed |
| WO-2023140640-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | 한양대학교 산학협력단 | 2023-07-27 | — | — | WO | disclosed |
| WO-2023140640-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | 한양대학교 산학협력단 | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101023-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | ERBB2, ERBB3, FGFR2 | CDK2 79/4885CCNA2 577/4885CDK9 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.