⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528642 | 0.72 | — | — | |
| SCHEMBL360654 | 0.68 | — | — | |
| SCHEMBL1144798 | 0.67 | — | — | |
| SCHEMBL9190792 | 0.65 | — | — | |
| SCHEMBL25183095 | 0.62 | — | — | |
| SCHEMBL24783606 | 0.61 | — | — | |
| SCHEMBL1897021 | 0.61 | — | — | |
| SCHEMBL25419072 | 0.59 | — | — | |
| SCHEMBL14118553 | 0.59 | — | — | |
| SCHEMBL18894340 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212153-A1 | LACTAMS AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | GENENTECH, INC. (US) | 2023-07-06 | — | — | US | disclosed |