Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855195 | 0.91 | HPGD (0.56) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL2675605 | 0.87 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL2675610 | 0.87 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL2282810 | 0.82 | KMT2A (0.58) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3751574 | 0.82 | KMT2A (0.58) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL586866 | 0.81 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL586865 | 0.81 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL895126 | 0.81 | KMT2A (0.53) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL23850295 | 0.81 | KMT2A (0.53) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL895125 | 0.81 | KMT2A (0.53) | KMT2AMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134765-A1 | FIVE-MEMBERED-RING-CONTAINING DERIVATIVES, PREPARATION METHOD THEREFOR, AND USES THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |