Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386814 | 0.79 | TSHR (0.46) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL10698134 | 0.77 | — | — | |
| SCHEMBL4952777 | 0.75 | TSHR (0.56) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL30285305 | 0.72 | TSHR (0.41) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL29424 | 0.72 | — | — | |
| SCHEMBL16613180 | 0.71 | TSHR (0.43) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL10818039 | 0.71 | TSHR (0.39) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL30604 | 0.70 | — | — | |
| SCHEMBL5708695 | 0.70 | — | — | |
| SCHEMBL170795 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593257-B2 | Functionalized metal-containing particles and methods of making the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20140315025-A1 | FUNCTIONALIZED METAL-CONTAINING PARTICLES AND METHODS OF MAKING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2014-10-23 | — | — | US | disclosed |
| US-8088252-B2 | Salt-sensitive cationic polymeric binders for nonwoven webs and method of making the same | CELANESE INTERNATIONAL CORPORATION | 2012-01-03 | — | — | US | disclosed |
| US-7989545-B2 | Salt-sensitive binders for nonwoven webs and method of making same | Celanese International Corporations (US) | 2011-08-02 | — | — | US | disclosed |
| US-20110146927-A1 | Method of making salt-sensitive binders and nonwoven webs | PROFOUND MEDICAL INC. (CA) | 2011-06-23 | — | — | US | disclosed |
| EP-2272880-A1 | Salt-sensitive binders for nonwoven webs and method of making same | Celanese International Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20070173594-A1 | Salt-sensitive binders for nonwoven webs and method of making same | CELANESE INTERNATIONAL CORPORATION | 2007-07-26 | — | — | US | disclosed |