Methacrylic Acid

Methacrylic Acid

SCHEMBL25317405

C=C(C)C(=O)O.CC(=CC(C)C)C(=O)O

nearest known ligand 0.35

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.35
GRIA2 P42262 2/20 0.35
GRIA4 P48058 2/20 0.35
GRIK3 Q13003 2/20 0.35
GRIK5 Q16478 2/20 0.35
GRIA1 P42261 1/20 0.35
GRIK2 Q13002 1/20 0.35
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.31
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31
APEX1 P27695 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21716 0.90
SCHEMBL21714 0.90
SCHEMBL6573659 0.90
Acetic Acid SCHEMBL10488048 0.87 FFAR3 (0.39) GRIK1GRIA2GRIA4GRIK3GRIK5
Methacrylic Acid SCHEMBL28170314 0.85 TDP1 (0.44) GRIK1GRIA2GRIA4GRIK3GRIK5
Methacrylic Acid SCHEMBL4288229 0.84 TP53 (0.32) TDP1TSHRPTGS1AKR1C3
SCHEMBL29801608 0.82 TSHR (0.36) TSHR
Methacrylic Acid SCHEMBL1137580 0.79
Methacrylic Acid SCHEMBL9938066 0.77 FFAR3 (0.39) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL8726425 0.76 PTGS1 (0.37) GRIK1GRIA2GRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4217326-A1 USE OF A REACTIVE LIQUID APPLIED ROOF WATERPROOFING PRODUCT FOR PRODUCING A ROOFING MEMBRANE Remmers GmbH (DE) 2023-08-02 EP disclosed