SCHEMBL25317679

SCHEMBL25317679

CCOC(=O)OCn1c(Br)c2c3c(cccc31)C1=C[C@@H](C(=O)N(CC)CC)CN(C)[C@@H]1C2

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 10/20 0.73
HTR2C P28335 4/20 0.73
HTR2B P41595 3/20 0.73
HTR7 P34969 3/20 0.61
HTR6 P50406 3/20 0.61
DRD2 P14416 3/20 0.53
HTR1A P08908 2/20 0.53
HRH1 P35367 2/20 0.53
DRD3 P35462 2/20 0.53
ADRB2 P07550 1/20 0.53
ADRB1 P08588 1/20 0.53
DRD4 P21917 1/20 0.53
DRD5 P21918 1/20 0.53
HTR1D P28221 1/20 0.53
HTR1E P28566 1/20 0.53
HTR5A P47898 1/20 0.53
CXCR3 P49682 4/20 0.49
DRD1 P21728 2/20 0.45
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30596828 1.00 HTR2A (0.73) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25893562 0.94 HTR2A (0.73) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25894161 0.90 HTR2A (0.77) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25893521 0.90 HTR2A (0.72) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25894099 0.87 HTR2A (0.81) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25316650 0.87 HTR2A (0.81) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25894378 0.87 HTR2A (0.77) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25890621 0.87 HTR2A (0.77) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL25315644 0.85 HTR2A (0.75) HTR2AHTR2CHTR2BHTR7HTR6
SCHEMBL30596826 0.85 HTR2A (0.75) HTR2AHTR2CHTR2BHTR7HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129064-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) TERRAN BIOSCIENCES INC. 2025-04-24 US disclosed
WO-2023141636-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) TERRAN BIOSCIENCES INC. (US) 2023-07-27 WO disclosed
WO-2023141636-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) TERRAN BIOSCIENCES INC. (US) 2023-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129064-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) GBA2, GBA1, SLC18A2 HTR2A 9/4885HTR2C 16/4885HTR2B 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.