Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.83 |
| ▸ | ABL1 | P00519 | 14/20 | 0.78 |
| ▸ | SIK2 | Q9H0K1 | 12/20 | 0.78 |
| ▸ | SIK3 | Q9Y2K2 | 12/20 | 0.78 |
| ▸ | SIK1 | P57059 | 10/20 | 0.78 |
| ▸ | SRC | P12931 | 6/20 | 0.71 |
| ▸ | BCR | P11274 | 4/20 | 0.71 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.71 |
| ▸ | LCK | P06239 | 2/20 | 0.71 |
| ▸ | FYN | P06241 | 2/20 | 0.71 |
| ▸ | CSF1R | P07333 | 2/20 | 0.71 |
| ▸ | YES1 | P07947 | 2/20 | 0.71 |
| ▸ | LYN | P07948 | 2/20 | 0.71 |
| ▸ | RET | P07949 | 2/20 | 0.71 |
| ▸ | HCK | P08631 | 2/20 | 0.71 |
| ▸ | KIT | P10721 | 2/20 | 0.71 |
| ▸ | BRAF | P15056 | 2/20 | 0.71 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.71 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634941 | 0.91 | PKMYT1 (1.00) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL18231278 | 0.91 | PKMYT1 (1.00) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL20537284 | 0.91 | PKMYT1 (0.85) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL28548985 | 0.88 | PKMYT1 (0.88) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL21875035 | 0.88 | ABL1 (1.00) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL31634943 | 0.87 | PKMYT1 (0.79) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL14416602 | 0.87 | PKMYT1 (0.79) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL23987824 | 0.85 | PKMYT1 (0.79) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL31307337 | 0.85 | ABL1 (0.74) | PKMYT1ABL1SIK2SIK3SIK1 | |
| SCHEMBL23987821 | 0.85 | ABL1 (0.74) | PKMYT1ABL1SIK2SIK3SIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230235062-A1 | TARGETED BINDING AGENTS AGAINST B7-H1 | MEDIMMUNE LTD (GB) | 2023-07-27 | — | — | US | disclosed |