Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 7/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31272060 | 1.00 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31271908 | 1.00 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL25318500 | 1.00 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31272009 | 1.00 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL29849301 | 0.95 | S1PR1 (0.46) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL30836851 | 0.95 | S1PR1 (0.46) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31203981 | 0.94 | PAOX (0.46) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31204082 | 0.94 | PAOX (0.46) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL25412654 | 0.94 | PAOX (0.46) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL31204187 | 0.94 | PAOX (0.46) | S1PR2S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188020-A1 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | ACUITAS THERAPEUTICS INC (CA) | 2025-06-12 | — | — | US | disclosed |
| US-12129223-B2 | Lipids for use in lipid nanoparticle formulations | Acuitas Therapeutics, Inc. (CA) | 2024-10-29 | — | — | US | disclosed |
| EP-4448485-A2 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2024-10-23 | — | — | EP | disclosed |
| US-20230295075-A1 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295075-A1 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295075-A1 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2023-09-21 | — | — | US | disclosed |
| WO-2023114943-A2 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295075-A1 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | PHOSPHO1, SGMS1, NPC1 | S1PR2 181/4885S1PR4 237/4885S1PR1 169/4885 |
| US-20250188020-A1 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | PHOSPHO1, SGMS1, NPC1 | S1PR2 181/4885S1PR4 237/4885S1PR1 169/4885 |
| US-12129223-B2 | Lipids for use in lipid nanoparticle formulations | PHOSPHO1, SGMS1, NPC1 | S1PR2 181/4885S1PR4 237/4885S1PR1 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.