Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551523 | 1.00 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL30551031 | 0.96 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL25319343 | 0.96 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL25319349 | 0.96 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL30551015 | 0.90 | PRMT5 (0.39) | PRMT5 | |
| SCHEMBL25321403 | 0.90 | PRMT5 (0.39) | PRMT5 | |
| SCHEMBL30551569 | 0.88 | PRMT5 (0.45) | PRMT5WDR77 | |
| SCHEMBL25322942 | 0.88 | PRMT5 (0.45) | PRMT5WDR77 | |
| SCHEMBL25322939 | 0.88 | PRMT5 (0.45) | PRMT5WDR77 | |
| SCHEMBL25324708 | 0.85 | KDM1A (0.39) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |