Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 12/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543146 | 1.00 | CYP2C19 (0.44) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL30509465 | 0.85 | CYP2C19 (0.46) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL30543160 | 0.85 | CYP2C19 (0.46) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL25323786 | 0.85 | CYP2C19 (0.46) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL25322767 | 0.85 | CYP2C19 (0.46) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL25323498 | 0.80 | CYP2C19 (0.41) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL30543174 | 0.80 | CYP2C19 (0.41) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL25324807 | 0.80 | CYP2C19 (0.41) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL25324146 | 0.80 | CYP2C19 (0.41) | CYP2C19HTR6L3MBTL1METPIK3C3 | |
| SCHEMBL30543162 | 0.80 | CYP2C19 (0.41) | CYP2C19HTR6L3MBTL1METPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK2A1 | CYP2C19 3167/4885HTR6 2574/4885L3MBTL1 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.