Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.60 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 6/20 | 0.43 |
| ▸ | CDC42BPA | Q5VT25 | 5/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543182 | 1.00 | LRRK2 (0.60) | LRRK2CDK2CDK9CDK5CCNT1 | |
| SCHEMBL20757525 | 0.79 | LRRK2 (0.53) | LRRK2CDK2CDK9CDK5CCNT1 | |
| SCHEMBL2693766 | 0.79 | LRRK2 (0.53) | LRRK2CDK2CDK9CDK5CCNT1 | |
| Hydrochloric Acid SCHEMBL27167150 | 0.78 | LRRK2 (0.51) | LRRK2CDK2CDK9CDK5CCNT1 | |
| Hydrochloric Acid SCHEMBL30705239 | 0.78 | LRRK2 (0.51) | LRRK2CDK2CDK9CDK5CCNT1 | |
| SCHEMBL16765827 | 0.76 | CHEK1 (0.51) | LRRK2ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL2694073 | 0.76 | LRRK2 (0.50) | LRRK2CDK2CDK9CDK5CCNT1 | |
| SCHEMBL2696119 | 0.76 | LRRK2 (0.50) | LRRK2CDK2CDK9CDK5CCNT1 | |
| SCHEMBL2105745 | 0.76 | LRRK2 (1.00) | LRRK2ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL30543157 | 0.76 | LRRK2 (1.00) | LRRK2ROCK2ROCK1CDC42BPBCDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK2A1 | LRRK2 787/4885CDK2 115/4885CDK9 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.