Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326222 | 1.00 | NR1H2 (0.47) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL25326942 | 0.95 | NR1H2 (0.45) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL25326937 | 0.95 | NR1H2 (0.45) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL30522950 | 0.91 | NR1H2 (0.41) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL30522915 | 0.90 | NR1H2 (0.40) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL25326039 | 0.88 | NR1H2 (0.39) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL25326035 | 0.88 | NR1H2 (0.39) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL30522933 | 0.86 | NR1H2 (0.39) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL12668388 | 0.84 | NR1H2 (0.56) | NR1H2NR1H3RIPK1RORCABHD6 | |
| SCHEMBL3188043 | 0.84 | NR1H2 (0.56) | NR1H2NR1H3RIPK1RORCABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282749-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-09-11 | — | — | US | disclosed |
| EP-4469445-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282749-A1 | COMPOUNDS AND METHODS OF USE | CYP1B1, CYP2C19, UGT1A1 | NR1H2 271/4885NR1H3 252/4885RIPK1 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.