Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334667 | 0.88 | EPHX1 (0.49) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL4719490 | 0.87 | GAA (0.59) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL13387564 | 0.87 | GAA (0.59) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL27688525 | 0.85 | GAA (0.54) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL30241859 | 0.84 | TSHR (0.53) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL16526220 | 0.82 | GAA (0.66) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL8259162 | 0.81 | GAA (0.54) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL4282204 | 0.81 | GAA (0.54) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL8260235 | 0.81 | GAA (0.54) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL2575225 | 0.81 | GAA (0.54) | GAAMAPK1HTTSMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147531-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |