Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523039 | 1.00 | TACR1 (0.37) | TACR1FABP7PRMT5SCN9ARIPK1 | |
| SCHEMBL30522989 | 0.96 | TACR1 (0.38) | TACR1FABP7PRMT5SCN9ARIPK1 | |
| SCHEMBL25325851 | 0.96 | TACR1 (0.38) | TACR1FABP7PRMT5SCN9ARIPK1 | |
| SCHEMBL25329263 | 0.95 | FABP7 (0.38) | TACR1FABP7PRMT5SCN9ARIPK1 | |
| SCHEMBL25329259 | 0.95 | FABP7 (0.38) | TACR1FABP7PRMT5SCN9ARIPK1 | |
| SCHEMBL25327878 | 0.91 | FABP7 (0.37) | TACR1FABP7SCN9ARIPK1PDK1 | |
| SCHEMBL25327880 | 0.91 | FABP7 (0.37) | TACR1FABP7SCN9ARIPK1PDK1 | |
| SCHEMBL25327418 | 0.88 | FABP7 (0.32) | TACR1FABP7RIPK1PDK1PDK2 | |
| SCHEMBL25327731 | 0.85 | PRMT5 (0.41) | PRMT5RIPK1WDR77 | |
| SCHEMBL25327730 | 0.85 | PRMT5 (0.41) | PRMT5RIPK1WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |