Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.68 |
| ▸ | CCNK | O75909 | 10/20 | 0.68 |
| ▸ | CDK12 | Q9NYV4 | 10/20 | 0.68 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.68 |
| ▸ | CDK9 | P50750 | 8/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.68 |
| ▸ | CDK7 | P50613 | 9/20 | 0.66 |
| ▸ | CCNH | P51946 | 8/20 | 0.66 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.66 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 9/20 | 0.63 |
| ▸ | JUN | P05412 | 8/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328906 | 1.00 | CDK2 (0.68) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25330852 | 0.91 | CDK2 (0.62) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25330857 | 0.91 | CDK2 (0.62) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25328949 | 0.90 | CCNK (0.75) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25327407 | 0.88 | CDK2 (0.62) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25328942 | 0.87 | MAPK8 (0.70) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25328939 | 0.87 | MAPK8 (0.70) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25329278 | 0.87 | CDK2 (0.58) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25329283 | 0.87 | CDK2 (0.58) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL6039764 | 0.87 | CDK2 (0.78) | CDK2CCNKCDK12CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |