SCHEMBL25329327 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CDK7	P50613	14/20	0.89

▸	CCNH	P51946	14/20	0.89

▸	CCNK	O75909	14/20	0.89

▸	CDK12	Q9NYV4	14/20	0.89

▸	CCNE1	P24864	14/20	0.89

▸	CDK2	P24941	14/20	0.89

▸	CCNT1	O60563	12/20	0.89

▸	CDK9	P50750	12/20	0.89

▸	MNAT1	P51948	12/20	0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25329325	1.00	CDK7 (0.89)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL24839343	0.94	CCNK (1.00)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL29498427	0.94	CCNK (1.00)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL30260874	0.93	CCNK (0.94)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL25327884	0.87	CCNT1 (0.69)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL25327879	0.87	CCNT1 (0.69)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL30524024	0.87	CCNT1 (0.69)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL24839872	0.87	CDK7 (1.00)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL24839878	0.87	CDK7 (1.00)	CDK7CCNHCCNKCDK12CCNE1
SCHEMBL24839707	0.87	CDK7 (1.00)	CDK7CCNHCCNKCDK12CCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023143482-A1	2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF	上海辉启生物医药科技有限公司	2023-08-03	—	—	WO	disclosed