⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328 | 0.82 | — | — | |
| SCHEMBL28907156 | 0.77 | — | — | |
| SCHEMBL28818979 | 0.77 | — | — | |
| SCHEMBL19637922 | 0.74 | — | — | |
| SCHEMBL5760792 | 0.58 | — | — | |
| SCHEMBL411 | 0.58 | — | — | |
| SCHEMBL497416 | 0.58 | — | — | |
| SCHEMBL887973 | 0.58 | — | — | |
| SCHEMBL19715 | 0.58 | — | — | |
| Phosphine SCHEMBL5862962 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060047-A | Fluoro polyhydroxy indolizidine compound, pharmaceutically acceptable salt thereof, synthesis method, glycosidase inhibitor and application | 中国科学院化学研究所 | 2024-12-03 | — | — | CN | claimed |
| CN-114560760-B | Synthesis method of euphorbiaceae diterpene Pepluanol A | 浙江大学杭州国际科创中心 | 2024-05-17 | — | — | CN | claimed |
| WO-2023142618-A1 | SYNTHESIS METHOD FOR EUPHORBIA DITERPENOID PEPLUANOL A | 浙江大学杭州国际科创中心 | 2023-08-03 | — | — | WO | claimed |
| CN-114560760-A | Method for synthesizing diterpene Pepluanol A in Euphorbiaceae | 浙江大学杭州国际科创中心 | 2022-05-31 | — | — | CN | claimed |
| CN-119060047-A | Fluoro polyhydroxy indolizidine compound, pharmaceutically acceptable salt thereof, synthesis method, glycosidase inhibitor and application | 中国科学院化学研究所 | 2024-12-03 | — | — | CN | disclosed |
| CN-114560760-B | Synthesis method of euphorbiaceae diterpene Pepluanol A | 浙江大学杭州国际科创中心 | 2024-05-17 | — | — | CN | disclosed |
| WO-2023142618-A1 | SYNTHESIS METHOD FOR EUPHORBIA DITERPENOID PEPLUANOL A | 浙江大学杭州国际科创中心 | 2023-08-03 | — | — | WO | disclosed |
| CN-114560760-A | Method for synthesizing diterpene Pepluanol A in Euphorbiaceae | 浙江大学杭州国际科创中心 | 2022-05-31 | — | — | CN | disclosed |
| CN-109952301-B | 5-HT2C receptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2022-03-25 | — | — | CN | disclosed |