Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 14/20 | 0.86 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.86 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.86 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.65 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16037395 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL16037838 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL16037400 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL16037841 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL13260245 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL16037401 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL18558637 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL16037398 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL16037840 | 1.00 | PTGFR (0.86) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL19420746 | 0.94 | PTGFR (0.76) | PTGFRABCC4ABCB11PTGER3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218759-A2 | COMBINATION THERAPY | Aerie Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |