Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 15/20 | 0.51 |
| ▸ | CDK7 | P50613 | 8/20 | 0.51 |
| ▸ | CCNH | P51946 | 8/20 | 0.51 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.51 |
| ▸ | CDK2 | P24941 | 13/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.47 |
| ▸ | CDK9 | P50750 | 8/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21188533 | 0.88 | CDK2 (0.53) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL29083554 | 0.88 | CDK2 (0.53) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL29749300 | 0.88 | CDK2 (0.53) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25329315 | 0.86 | CCNK (0.54) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25331384 | 0.86 | CCNK (0.54) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25328993 | 0.83 | CDK2 (0.64) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25328988 | 0.83 | CDK2 (0.64) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25329237 | 0.83 | MAPK8 (0.60) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL31006791 | 0.83 | MAPK8 (0.60) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25329239 | 0.83 | MAPK8 (0.60) | CCNKCDK12CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |