Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25330533 | 1.00 | GRIN2B (0.33) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL14488305 | 0.86 | USP2 (0.35) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL10174274 | 0.84 | USP2 (0.34) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL28371753 | 0.84 | USP2 (0.34) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL6188259 | 0.83 | USP2 (0.38) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL16594444 | 0.83 | USP2 (0.38) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL15023539 | 0.83 | NR1H2 (0.34) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL705951 | 0.81 | GRIN2B (0.33) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL502555 | 0.81 | GRIN2B (0.33) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL6919845 | 0.81 | GRIN2B (0.33) | GRIN2BGRIN2CUSP2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138583-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |