⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330866 | 0.89 | — | — | |
| SCHEMBL373016 | 0.89 | CYP1A2 (0.38) | — | |
| SCHEMBL2533761 | 0.87 | CYP2C19 (0.38) | — | |
| SCHEMBL2532414 | 0.87 | CYP2C19 (0.38) | — | |
| SCHEMBL410868 | 0.73 | — | — | |
| SCHEMBL16684412 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL1661800 | 0.71 | — | — | |
| SCHEMBL19867191 | 0.71 | — | — | |
| SCHEMBL3420264 | 0.71 | — | — | |
| SCHEMBL18125940 | 0.71 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246478-B2 | Polyene macrolide derivative | SHIONOGI & CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-2389190-A2 | FGF21 DERIVATIVES WITH ALBUMIN BINDER A-B-C-D-E- AND THEIR USE | Novo Nordisk A/S (DK) | 2011-11-30 | — | — | EP | disclosed |
| US-20110253729-A1 | CONTAINER FOR DISPENSING FLUID | RING THOMAS J | 2011-10-20 | — | — | US | disclosed |
| WO-2010084169-A2 | FGF21 DERIVATIVES WITH ALBUMIN BINDER A-B-C-D-E- AND THEIR USE | NOVO NORDISK A/S (DK) | 2010-07-29 | — | — | WO | disclosed |