Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 13/20 | 0.84 |
| ▸ | BTK | Q06187 | 6/20 | 0.84 |
| ▸ | KDR | P35968 | 5/20 | 0.84 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.84 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.84 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.84 |
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515832 | 1.00 | FGFR2 (0.84) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL25334852 | 1.00 | FGFR2 (0.84) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL29064253 | 0.93 | FGFR2 (0.82) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL30515759 | 0.93 | FGFR2 (0.82) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL29063670 | 0.92 | FGFR2 (0.76) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL30516058 | 0.92 | FGFR2 (0.76) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL29063684 | 0.92 | FGFR2 (0.76) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL29063800 | 0.91 | FGFR2 (0.78) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL30515879 | 0.91 | FGFR2 (0.78) | FGFR2BTKKDRFGFR1FGFR4 | |
| SCHEMBL29063808 | 0.91 | FGFR2 (0.78) | FGFR2BTKKDRFGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143514-A1 | PROPYLENE KETONE-CONTAINING BIOINHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-116514806-A | Biological inhibitor containing acrylketone, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |