SCHEMBL2533709

SCHEMBL2533709

C=C(C)C(C)=CCCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.43
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 5/20 0.42
ALDH1A1 P00352 1/20 0.35
FAAH O00519 1/20 0.34
TRPV1 Q8NER1 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX15 P16050 1/20 0.33
APEX1 P27695 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2533707 1.00 EP300 (0.43) EP300MEN1CYP3A4KMT2ATSHR
SCHEMBL3349275 0.98 EP300 (0.47) EP300MEN1CYP3A4KMT2ATSHR
SCHEMBL3349280 0.98 EP300 (0.47) EP300MEN1CYP3A4KMT2ATSHR
SCHEMBL2529563 0.93 TSHR (0.42) EP300MEN1CYP3A4KMT2ATSHR
SCHEMBL2529564 0.93 TSHR (0.42) EP300MEN1CYP3A4KMT2ATSHR
SCHEMBL31295871 0.91 TSHR (0.40) EP300MEN1CYP3A4KMT2ATSHR
SCHEMBL2535783 0.82
SCHEMBL2535782 0.82
SCHEMBL19642855 0.81 TSHR (0.42) CYP3A4TSHRALDH1A1USP2LMNA
Methacrylic Acid SCHEMBL2023997 0.80 EP300 (0.58) EP300KMT2ATSHRFAAHGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250208-A1 SYNTHESIS OF ISOPRENE-BUTADIENE COPOLYMER RUBBERS MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2023-08-10 US disclosed
US-11597790-B2 Synthesis of isoprene-butadiene copolymer rubbers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2023-03-07 US disclosed
US-20210189040-A1 SYNTHESIS OF ISOPRENE-BUTADIENE COPOLYMER RUBBERS MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2021-06-24 US disclosed
EP-3838932-A1 SYNTHESIS OF ISOPRENE-BUTADIENE COPOLYMER RUBBERS The Goodyear Tire & Rubber Company (US) 2021-06-23 EP disclosed
CN-113004461-A Synthesis of isoprene-butadiene copolymer rubber 固特异轮胎和橡胶公司 2021-06-22 CN disclosed
EP-1522901-B1 Toner CANON KK (JP) 2016-03-16 EP disclosed
US-8293447-B2 Toner CANON KABUSHIKI KAISHA (JP) 2012-10-23 US disclosed
US-20110256480-A1 TONER CANON KABUSHIKI KAISHA (JP) 2011-10-20 US disclosed
US-7842447-B2 Toner CANON KABUSHIKI KAISHA (JP) 2010-11-30 US disclosed
CN-100428059-C Toner CANON KK (JP) 2008-10-22 CN disclosed
US-5049620-A High modulus rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US disclosed
EP-0434596-A2 High modulus rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-06-26 EP disclosed
CN-1005979-B SELF-EMULSIVE RESIN POWDER 固特异轮胎和橡胶公司 1989-12-06 CN disclosed
EP-0336874-A1 Inverse phase polymerization THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-10-11 EP disclosed
US-4855402-A Self-emulsifiable resin powder THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-08-08 US disclosed
US-4777198-A Resin powder of unsaturated carboxyl monomer and sulfate or sulfonic salt THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-10-11 US disclosed
EP-0236253-A1 Process for bulk polymerizing butadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-09 EP disclosed
EP-0226527-A2 Self-emulsifiable resin powder THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-06-24 EP disclosed
CN-86107905-A SELF-EMULSIVE RESIN POWDER GOODYEAR TIRE & RUBBER (US) 1987-05-27 CN disclosed
US-3985677-A POLYMERIZATION OF BUTADIENE ANDOR BUTADIENE WITH DIOLEFINS WITH HIGH CIS-1,4 ADDITION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-10-12 US disclosed