Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GPX4 | P36969 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337272 | 1.00 | MEN1 (0.32) | MEN1KMT2AGPX4SMN1; SMN2LMNA | |
| SCHEMBL29480900 | 0.87 | CNR2 (0.36) | — | |
| SCHEMBL25596924 | 0.87 | ESR1 (0.33) | LMNAGLAL3MBTL1 | |
| SCHEMBL25694815 | 0.87 | ESR1 (0.33) | LMNAGLAL3MBTL1 | |
| SCHEMBL19369088 | 0.85 | IDO1 (0.31) | MEN1 | |
| SCHEMBL25337050 | 0.85 | MEN1 (0.34) | MEN1SMN1; SMN2LMNA | |
| SCHEMBL31578956 | 0.85 | KDM4E (0.36) | MEN1SMN1; SMN2LMNA | |
| SCHEMBL25337054 | 0.85 | MEN1 (0.34) | MEN1SMN1; SMN2LMNA | |
| SCHEMBL30405771 | 0.85 | MEN1 (0.34) | MEN1SMN1; SMN2LMNA | |
| SCHEMBL30405349 | 0.85 | MEN1 (0.34) | MEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150635-A1 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH MENIN INHIBITORS AND P-GLYCOPROTEIN INHIBITORS | KURA ONCOLOGY, INC. (US) | 2023-08-10 | — | — | WO | disclosed |