Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | AIMP2 | Q13155 | 10/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834305 | 0.88 | MAPT (1.00) | MAPTAIMP2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7837183 | 0.80 | MAPT (0.82) | MAPTAIMP2HTTALDH1A1MEN1 | |
| SCHEMBL6204950 | 0.80 | MEN1 (0.67) | MAPTHTTMTNR1ATSHRALDH1A1 | |
| SCHEMBL7829246 | 0.79 | MAPT (0.83) | MAPTAIMP2HTTCYP2C19CYP1A2 | |
| SCHEMBL1854450 | 0.78 | NPY5R (0.61) | MAPTHTTPKMALDH1A1KDM4E | |
| SCHEMBL7828214 | 0.77 | MAPT (0.70) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7824584 | 0.77 | MAPT (0.80) | MAPTAIMP2MTNR1A | |
| SCHEMBL7838051 | 0.76 | MAPT (0.77) | MAPTMTNR1AALDH1A1KDM4EMEN1 | |
| SCHEMBL7838049 | 0.76 | MAPT (0.77) | MAPTMTNR1AALDH1A1KDM4EMEN1 | |
| SCHEMBL7817707 | 0.76 | MAPT (0.68) | MAPTALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146244-A1 | BENZODIOXANE DERIVATIVE COMPOUNDS AND MEDICAL USE THEREOF | 재단법인 한국파스퇴르연구소 | 2023-08-03 | — | — | WO | claimed |
| WO-2023146244-A1 | BENZODIOXANE DERIVATIVE COMPOUNDS AND MEDICAL USE THEREOF | 재단법인 한국파스퇴르연구소 | 2023-08-03 | — | — | WO | disclosed |