Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.65 |
| ▸ | CA1 | P00915 | 5/20 | 0.65 |
| ▸ | CA2 | P00918 | 5/20 | 0.65 |
| ▸ | CA7 | P43166 | 5/20 | 0.65 |
| ▸ | CA9 | Q16790 | 5/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322149 | 0.96 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28451530 | 0.94 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9129292 | 0.88 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8167665 | 0.88 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL796110 | 0.88 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28446948 | 0.86 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15959314 | 0.86 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24894280 | 0.85 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1952844 | 0.85 | CA1 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24894581 | 0.85 | CA12 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044098-B2 | Use of e.g. 2,4-dihydroxybenzoic acid or 3,4,5-trihydroxybenzoic acid or esters thereof; hepatitis B virus (HBV), papillomavirus and/or herpes virus | SHENGHUA GUANGZHOU PHARMACEUTICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2011-10-25 | — | — | US | disclosed |
| US-20080119550-A1 | Use of e.g. 2,4-dihydroxybenzoic acid or 3,4,5-trihydroxybenzoic acid or esters thereof; hepatitis B virus (HBV), papillomavirus and/or herpes virus | SHENGHUA GUANGZHOU PHARMACEUTICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119550-A1 | Use of e.g. 2,4-dihydroxybenzoic acid or 3,4,5-trihydroxybenzoic acid or esters thereof; hepatitis B virus (HBV), papillomavirus and/or herpes virus | ETV1, ETV6, CYP8B1 | CA12 1220/4885CA1 2914/4885CA2 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.