SCHEMBL2534280

SCHEMBL2534280

C[Si](C)=[Ti](C)(C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.37
KDM4E B2RXH2 2/20 0.34
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CHRM2 P08172 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
NFKB1 P19838 1/20 0.34
CHRM3 P20309 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373281 0.87 HTR2A (0.33) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL8754615 0.81 HTR2A (0.34) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL393668 0.80 HTR2A (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL3382736 0.77 BRD4 (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL2534262 0.77 BRD4 (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL3383324 0.77 BRD4 (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL3381692 0.77 BRD4 (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL3383375 0.77 BRD4 (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL7756041 0.77 BRD4 (0.36) HTR2AKDM4EBRD4CCL2LMNA
SCHEMBL21436081 0.76 KDM4E (0.32) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8044144-B2 Resin composition, transparent film or sheet having elasticity recovering property, and wrap film PRIME POLYMER CO., LTD. (JP) 2011-10-25 US disclosed
US-20090012238-A1 RESIN COMPOSITION, TRANSPARENT FILM OR SHEET HAVING ELASTICITY RECOVERING PROPERTY, AND WRAP FILM PRIME POLYMER CO., LTD (JP) 2009-01-08 US disclosed
US-7259215-B2 Process for producing propylene/ethylene block copolymer and propylene/ethylene block copolymer IDEMITSU KOSAN CO., LTD. (JP) 2007-08-21 US disclosed
US-20060014909-A1 Process for producing propylene/ethylene block copolymer and propylene/ethylene block copolymer IDEMITSU KOSAN CO., LTD. (JP) 2006-01-19 US disclosed
EP-1561762-A1 PROCESS FOR PRODUCING PROPYLENE/ETHYLENE BLOCK COPOLYMER AND PROPYLENE/ETHYLENE BLOCK COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-08-10 EP disclosed
EP-0659774-B1 Process for producing styrenic polymer IDEMITSU KOSAN CO (JP) 1999-03-03 EP disclosed
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP disclosed
US-5747613-A Process for producing aromatic vinyl compound-based copolymer IDEMITSU KOSAN CO., LTD. (JP) 1998-05-05 US disclosed
US-5623034-A Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1997-04-22 US disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0497207-B1 Process for purification of styrenic polymer IDEMITSU KOSAN CO (JP) 1996-11-20 EP disclosed
EP-0707014-A1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-04-17 EP disclosed
EP-0659774-A2 Process for producing styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-06-28 EP disclosed