SCHEMBL25344898

SCHEMBL25344898

C#CCCCCCCOS(C)(=O)=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
KDM4E B2RXH2 1/20 0.62
USP2 O75604 1/20 0.62
ALDH1A1 P00352 1/20 0.62
LMNA P02545 1/20 0.62
MMP9 P14780 1/20 0.62
ALOX15 P16050 1/20 0.62
CA2 P00918 16/20 0.42
CA9 Q16790 15/20 0.42
CA1 P00915 15/20 0.38
CA12 O43570 5/20 0.38
CA7 P43166 5/20 0.38
CA14 Q9ULX7 5/20 0.38
CA3 P07451 4/20 0.38
CA4 P22748 4/20 0.38
CA6 P23280 4/20 0.38
CA5A P35218 4/20 0.38
CA5B Q9Y2D0 4/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27187302 1.00 TSHR (0.62) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL21070050 1.00 TSHR (0.62) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL10726607 1.00 TSHR (0.62) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL9253800 1.00 TSHR (0.62) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL15887083 1.00 TSHR (0.62) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL1142936 0.98 KDM4E (0.65) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL313345 0.91 USP2 (0.61) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL312544 0.82
SCHEMBL4952202 0.82 TSHR (0.94) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL8592211 0.82 TSHR (0.94) TSHRKDM4EUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712974-A2 STAT DEGRADERS AND USES THEREOF Recludix Pharma, Inc. (US) 2026-03-25 EP disclosed
EP-4709370-A2 STAT DEGRADERS AND USES THEREOF Recludix Pharma, Inc. (US) 2026-03-18 EP disclosed
WO-2024238603-A2 STAT DEGRADERS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2024-11-21 WO disclosed
WO-2024233639-A2 STAT DEGRADERS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2024-11-14 WO disclosed
WO-2023151635-A1 COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF 标新生物医药科技(上海)有限公司 2023-08-17 WO disclosed